December 10th 2011
NIAID News Release: Statement: NIH Discontinues Tenofovir Vaginal Gel in ‘VOICE’ HIV Prevention Study
A large-scale clinical trial evaluating whether daily use of an antiretroviral-containing oral tablet or vaginal gel can prevent HIV infection in women is being modified because an interim review found that the gel, an investigational microbicide, was not effective among study participants.
On Nov. 17, an independent data and safety monitoring board (DSMB) recommended that the Vaginal and Oral Interventions to Control the Epidemic (VOICE) study evaluating daily use 1 percent tenofovir vaginal gel be discontinued because there was no difference in effect demonstrated between the drug-containing gel and a placebo gel.
Tags: Hiv, Vaginal Gel